自闭症谱系障碍中感觉处理的神经生物学

作者：

Cheung, PPP (Cheung, Phoebe Pui Pui)  ; Lau, BWM (Lau, Benson Wui Man)

摘要：

Altered sensory processing and perception has been one of the characteristics of autism spectrum disorder (ASD). In this chapter, we review the neural underpinnings of sensory abnormalities of ASD by examining the literature on clinical, behavioral and neurobiological evidence that underlies the main patterns of sensory integration function and dysfunction. Furthermore, neural differences in anatomy, function and connectivity of different regions underlying sensory processing are also discussed. We conclude that sensory integration intervention is built on the premise of neuroplasticity to improve function and behavior for individuals with ASD.

改变的感觉处理和感知一直是自闭症谱系障碍（ASD）的特征之一。在本章中，我们通过检查有关临床、行为和神经生物学证据的文献，来回顾ASD感觉异常的神经基础，以了解感觉整合功能和功能失调的主要模式。此外，还讨论了不同区域神经解剖、功能和连接性的神经差异，这些区域是感觉处理的基础。我们得出结论，感觉整合干预建立在神经可塑性的前提上，以改善ASD患者的功能和行为。